Horsenettle is found in sandy openings and can be a problem in pastures. Mature plants are perennials with spiny and hairy stems. Flowers may be white, violet, or blue in color, and the fruit produced turns yellow as it matures. The fruit is poisonous and has caused death in cattle.
Treating small, immature plants gives the best results, and there are several herbicides available, Milestone and GrazonNext both work well on Horsenettle, and retreatment may be necessary depending on the density of the plants.